Meld score mortality6/17/2023 Another significant risk factor for mortality was admission to the intensive care unit. The study also demonstrated that the most frequent cause of mortality was hepatorenal syndrome, followed by spontaneous bacterial peritonitis, hepatic encephalopathy, and pneumonia. 9 That reduction appears to be due to earlier detection of cirrhosis through noninvasive diagnostic methods and improved management of the associated complications. The authors concluded that there has been a significantly reduced hospital mortality rate in recent years. The study showed there was an overall hospital mortality rate in patients with ACLF of 11.6% 9 and a 27% decrease in hospital mortality during the period of 2006-2010, compared with the period of 2003-2005. 8Ī study conducted in Barcelona, Spain, evaluated 12,671 hospital admissions of patients with cirrhosis of the liver within the time frame of 2003 to 2010. 7 The CLIF model has better predictive values for mortality than the classic MELD and MELD-Na models. Its aims were to develop a clinical definition for ACLF and establish a model for evaluating the short-term risk of mortality in those patients. It is a prospective and multicenter study conducted by the European Consortium for the Study of Chronic Liver Failure (CLIF). The Chronic Liver Failure in Cirrhosis (CANONIC) study developed one such model. There are several models for predicting mortality in patients with acute-on-chronic liver failure (ACLF). 6 This variability is determined more by the degree of organ failure than by the severity of the liver disease. Nevertheless, when patients with cirrhosis of the liver are hospitalized, mortality increases significantly, ranging from 44 to 74%. 3 The conventional Child-Pugh 4 or MELD score 5 scales are also available to us and aid in establishing prognosis and prioritizing liver transplantation patients. 2įrom a practical viewpoint, we know that patients with decompensated cirrhosis have a worse outcome (median 2-year survival), compared with patients with compensated disease (median 9 to 12-year survival). 1 However, establishing prognosis in patients with cirrhosis of the liver is still a clinical challenge, due to its great variability and its dependence on many factors, such as etiology, liver function status, the presence and severity of portal hypertension, the possibility of treatment, and the potential development of hepatocellular carcinoma. See moreĬirrhosis of the liver continues to be a frequent cause of mortality worldwide, and is the twelfth cause of death in North America. The journal accepts original articles, scientific letters, review articles, clinical guidelines, consensuses, editorials, letters to the Editors, brief communications, and clinical images in Gastroenterology in Spanish and English for their publication. The scientific works include the areas of Clinical, Endoscopic, Surgical, and Pediatric Gastroenterology, along with related disciplines. The principal aim of the journal is to publish original work in the broad field of Gastroenterology, as well as to provide information on the specialty and related areas that is up-to-date and relevant. Its pages are open to the members of the Association, as well as to all members of the medical community interested in using this forum to publish their articles in accordance with the journal editorial policies. The Revista de Gastroenterología de México (Mexican Journal of Gastroenterology) is the official publication of the Asociación Mexicana de Gastroenterología (Mexican Association of Gastroenterology).
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